Introduction:

Myricetin is a naturally occurring flavonoid that can either be extracted from Southern Wax Myrtle, or it can be consumed in diet through a variety of foods such as red wine, berries, vegetables, and tea (Ristic, 2020). It is known for its antioxidant, anticancer, and anti-inflammatory properties. Currently, many research studies are looking into how Myricetin can help treat or slow the progression of Parkinson’s Disease, Alzheimer’s, and Dementia by reducing the cognitive decline associated with these diseases. One recent study looked into how Myricetin was able to improve the brain symptoms of Traumatic Brain Injury (TBI), such as cognitive disabilities, in rats that were induced with TBIs (Mirshekar et al., 2019). As well as being known for its ability to reduce oxidative stress induced damage on the central nervous system, Myricetin is also being researched for its potential antitumor properties, which may include modifying cancer hallmarks such as cell proliferation, apoptosis, and signaling pathways (Devi et al., 2015).

Future Research

●  Antitumor properties

●  Molecular mechanisms behind how it improves cognitive deficits

●  More clinical trials to observe its long-term effectiveness in humans

●  Study its neuroprotective properties

References

Agarwal P., Bennett, D. A., Booth, S. L., Holland, T. M., Leurgans, S. E., Morris, M. C., & Wang, Y. (2020). Dietary flavonols and risk of Alzheimer dementia [Abstract]. Neurology, 94(16), 1749-1756. doi:10.1212/wnl.0000000000008981

Ara, G., Afzal, M., Jyoti, S., Naz, F., Rahul, & Siddique, Y. H. (2019). Effect of Myricetin on the Loss of Dopaminergic Neurons in the Transgenic Drosophila Model of Parkinson’s Disease [Abstract]. Current Drug Therapy, 14(1), 58-64. doi:10.2174/1574885513666180529114546

Hara, Y. (2020, April 22). Can flavonols prevent Alzheimer's disease? Retrieved August 13, 2020, from

https://www.alzdiscovery.org/cognitive-vitality/blog/can-flavonols-prevent-alzheimers-disease

Mirshekar, M. A., Najafi, R., & Shabani, S, & Shahraki, M. (2019). The ameliorative effects of myricetin on neurobehavioral activity, electrophysiology, and biochemical changes in an animal model of traumatic brain injury [Abstract]. Learning and Motivation, 68, 101597. doi:10.1016/j.lmot.2019.101597

Myricetin 97.0+%, TCI AmericaTM [Digital image]. (n.d.). Retrieved August 12, 2020, from

https://www.fishersci.com/shop/products/myricetin-tci-america-2/M2131500MG

Ristic, A. (2020, January 03). Potential Myricetin Benefits + Sources & Side Effects. Retrieved June 22, 2020, from https://selfhacked.com/blog/myricetin-benefits/

SOURCE NATURALS Myricetin 100 Mg Tablet, 60 Count [Digital image]. (n.d.). Retrieved September 21, 2020, from

https://www.amazon.com/SOURCE-NATURALS-Myricetin-Tablet-Count/dp/B0014GZRNE

UF/IFAS Solutions. (n.d.). Waxmyrtle [Digital image]. Retrieved September 21, 2020, from https://nwdistrict.ifas.ufl.edu/hort/2015/11/05/waxmyrtle-an-overlooked-landscape-shrub/